{"id":1862,"date":"2018-08-14T11:19:37","date_gmt":"2018-08-14T04:19:37","guid":{"rendered":"http:\/\/stang.sc.mahidol.ac.th\/newresources\/?p=1862"},"modified":"2018-08-14T11:23:27","modified_gmt":"2018-08-14T04:23:27","slug":"biomolecular-kinetics-a-step-by-step-guide","status":"publish","type":"post","link":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/?p=1862","title":{"rendered":"Biomolecular kinetics : a step-by-step guide"},"content":{"rendered":"<p><a href=\"http:\/\/mulinet1.li.mahidol.ac.th\/record=b1481236a\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-1836 size-medium\" src=\"http:\/\/stang.sc.mahidol.ac.th\/newresources\/wp-content\/uploads\/2018\/08\/65636-234x300.jpg\" alt=\"\" width=\"234\" height=\"300\" \/><\/a><strong>AUTHOR<\/strong> :\u00a0 Bagshaw, C. R. (Clive Richard)<\/p>\n<p><strong>CALL NO<\/strong> :\u00a0 QU34 B149b 2017<\/p>\n<p><strong>IMPRINT <\/strong>:\u00a0\u00a0 Boca Raton, Fla. : CRC Press, c2017<!--more--><\/p>\n<p>This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics.<\/p>\n<p>Features<\/p>\n<ul>\n<li>Worked answers to exercises in the book are available to confirmed adopting instructors.<\/li>\n<li>Introduces the analytical rate equations for basic one and two-step reactions relevant to the interactions of macromolecules with ligands.<\/li>\n<li>Extends the analysis using the step-by-step approach of numerical integration and the &#8220;dice-rolling&#8221; approach of stochastic simulations.<\/li>\n<li>Discusses the theory and practice of elucidating biomolecular mechanisms, including enzyme action, protein folding, protein-nucleic acid interactions and molecular motors.<\/li>\n<li>Provides a comprehensive description of instruments and techniques for following transient reactions on a sub-second time scale and at the single-molecule level.<\/li>\n<li>Illustrates the analysis of reaction records using computer simulation and fitting, using commercial software and freeware.<\/li>\n<\/ul>\n<p>Source : <a href=\"http:\/\/www.crcpress.com\/Biomolecular-Kinetics-A-Step-by-Step-Guide\/Bagshaw\/p\/book\/9781498727235\">www.crcpress.com\/Biomolecular-Kinetics-A-Step-by-Step-Guide\/Bagshaw\/p\/book\/9781498727235<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>AUTHOR :\u00a0 Bagshaw, C. R. (Clive Richard) CALL NO :\u00a0 QU34 B149b 2017 IMPRINT :\u00a0\u00a0 Boca Raton, Fla. : CRC Press, c2017<\/p>\n","protected":false},"author":1,"featured_media":1836,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[574,368,575],"class_list":["post-1862","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new-book-releases","tag-biomolecular-kinetics","tag-enzymes","tag-kinetics"],"_links":{"self":[{"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/posts\/1862","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1862"}],"version-history":[{"count":2,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/posts\/1862\/revisions"}],"predecessor-version":[{"id":1864,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/posts\/1862\/revisions\/1864"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=\/wp\/v2\/media\/1836"}],"wp:attachment":[{"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1862"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1862"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stang.sc.mahidol.ac.th\/newresources\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1862"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}