Methods in molecular biophysics : structure, dynamics, function for biology and medicine
AUTHOR : Zaccai, Nathan R.
CALL NO : QT34 Z13m 2017
IMPRINT : Cambridge : Cambridge University Press, c2017
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.
- Provides comprehensive coverage and up-to-date treatment of the full range of physical methods used in current biological research as well as in medical physics, illustrated using real-world examples
- Each method includes a brief historical introduction, theoretical principles, applications, advantages and limitations, and concludes with a checklist of key ideas that summarize the important points for students
- Includes all the necessary background to ensure accessibility for biologists, physicists, and those with medical backgrounds
